Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mulberry (Morus alba) has a history of use in traditional medicine, particularly in Chinese and other Asian healing systems. In these traditions, mulberry leaves and extracts have been used to help “cool the blood” and address skin conditions that are thought to be related to inflammation or “heat,” such as psoriasis. While psoriasis is a chronic autoimmune skin disorder characterized by red, scaly patches, traditional practitioners have applied mulberry preparations topically or consumed them as teas to help relieve skin irritation and inflammation. The rationale is based largely on the plant’s reputed anti-inflammatory, antioxidant, and “detoxifying” properties.

However, scientific studies specifically investigating mulberry’s effects on psoriasis in humans are extremely limited. Some in vitro and animal studies suggest that mulberry extracts contain bioactive compounds (such as flavonoids and alkaloids) with anti-inflammatory and immunomodulatory effects, which could theoretically benefit inflammatory skin diseases. For example, certain extracts have shown inhibition of pro-inflammatory cytokines and oxidative stress markers in laboratory settings. But these findings have not been directly tested in clinical trials for psoriasis.

In summary, the use of mulberry for psoriasis is rooted mainly in traditional medicine practices, with limited laboratory evidence suggesting potential benefit. There is currently a lack of robust clinical data to scientifically validate its efficacy for this condition, so its use should be considered traditional and evidence for effectiveness rated low.

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