Evidence supporting the use of: Apigenin
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Apigenin is a natural flavonoid found in various plants, including parsley, celery, and chamomile. Its use in supporting or treating psoriasis is based on emerging scientific evidence rather than longstanding traditional application. Preclinical studies, primarily conducted in vitro (cell cultures) and in animal models, have demonstrated that apigenin exhibits anti-inflammatory, antioxidant, and immunomodulatory effects, which are relevant to the pathophysiology of psoriasis. For example, research has shown that apigenin can inhibit the production of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-17, which play key roles in the development and progression of psoriatic lesions (Li et al., 2018). Additionally, apigenin has been reported to suppress the activation of NF-κB, a transcription factor involved in inflammation and immune responses. However, there is a lack of robust clinical data in humans directly evaluating apigenin for psoriasis treatment. No large-scale randomized controlled trials have been published to date. The evidence for apigenin’s efficacy in psoriasis is therefore limited to preclinical studies, and more research is needed before it can be recommended as a standard or adjunctive therapy. In summary, while there is a scientific basis for investigating apigenin in psoriasis, current evidence supporting its use is preliminary and not yet sufficient for clinical recommendations.

More about Apigenin
More about Psoriasis

Other ingredients used for Psoriasis

alfalfa
algal oil
aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
Apple Cider Vinegar
Apigenin
Andrographolide
Avocado
Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
Cod Liver Oil
Cnidium
Centella asiatica
Cistus
Chirata
Cannabidiol
Copaiba Oil
Docosahexaenoic Acid
European Elder
Emu Oil
Eicosapentaenoic Acid
Ethyl Linoleate
Fumaric Acid
Ficus religiosa
Frankincense
Gallic Acid
Glycolic acid
Glucosylceramide
Glycyrrhetinic Acid
Glycyrrhizin
vegetable oil
walnut

Products containing Apigenin

We currently have no products on Caring Sunshine that contain this ingredient.