Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Omega-3 fatty acids have been studied for their potential role in preventing or reducing the recurrence of polyps, particularly colorectal adenomatous polyps, which are precursors to colorectal cancer. The scientific rationale is based on omega-3 fatty acids’ anti-inflammatory properties and their influence on cellular proliferation and apoptosis in the colon. Several observational studies and a few small clinical trials have suggested that higher intake of omega-3s, especially from fish, may be associated with a reduced risk of colorectal polyps. For instance, some studies observed that individuals with higher dietary omega-3 intake had fewer or smaller polyps detected during colonoscopy. However, the evidence is not robust. Randomized controlled trials specifically targeting polyp prevention with omega-3 supplementation are limited and have shown mixed results. Some trials have failed to demonstrate a significant reduction in polyp formation with omega-3 supplementation. A 2019 systematic review concluded that while there is some mechanistic and epidemiological support, clinical evidence remains insufficient to recommend omega-3s specifically for polyp prevention or treatment. Overall, omega-3s are not a standard therapy for polyps, but they are being researched for their potential chemopreventive effects. Thus, while there is a scientific basis for their investigation, the current level of evidence is low to moderate (rating: 2/5), and omega-3s should not be relied upon as a primary treatment or prevention strategy for polyps.

More about omega-3 fatty acids
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Other ingredients used for Polyps

Other health conditions supported by omega-3 fatty acids

Products containing omega-3 fatty acids

Nature's Sunshine Flax Seed Oil (With Lignans)