Evidence supporting the use of: Insulina
For the body system: Pancreatic Tail
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Insulin is a peptide hormone produced by the beta cells in the islets of Langerhans, which are located primarily in the tail region of the pancreas. Its primary physiological role is the regulation of glucose metabolism. In cases of type 1 diabetes mellitus, and sometimes in advanced type 2 diabetes, endogenous insulin production is insufficient or absent due to dysfunction or destruction of pancreatic beta cells. Exogenous insulin is administered to restore physiological glucose homeostasis, prevent the complications of hyperglycemia, and support overall metabolic function. The use of insulin to support the pancreatic system, specifically the endocrine function located in the pancreatic tail, is extensively validated in the scientific literature. Numerous clinical trials and decades of clinical practice have demonstrated that insulin therapy is effective and often essential for survival in individuals with type 1 diabetes, and for glycemic control in selected type 2 diabetes patients. Guidelines from major health organizations, including the American Diabetes Association and the World Health Organization, strongly endorse insulin as the standard of care for insulin-deficient diabetes. Thus, insulin is not only scientifically validated for supporting pancreatic endocrine function, especially when the tail’s beta cells are compromised, but is also a cornerstone of diabetes management.
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