Evidence supporting the use of: Vitamin B6
For the body system: Ovaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B6, also known as pyridoxine, has some scientific backing for its role in supporting aspects of ovarian health, particularly in relation to premenstrual syndrome (PMS). Several clinical studies have shown that vitamin B6 supplementation may help reduce symptoms of PMS, such as mood swings, irritability, and bloating, which are linked to fluctuations in ovarian hormone production. The likely mechanism involves vitamin B6’s role in neurotransmitter synthesis—especially serotonin—which can be affected by cyclic hormonal changes during the menstrual cycle.

Furthermore, vitamin B6 is involved in hormone metabolism, including the modulation of estrogen and progesterone, two key ovarian hormones. Some research suggests that vitamin B6 may help with luteal phase defects by supporting progesterone synthesis, although the evidence is not robust. Its use in polycystic ovary syndrome (PCOS) and other ovarian dysfunctions is less well established, with only limited supportive data.

Overall, there is moderate scientific evidence supporting vitamin B6's use to alleviate certain ovarian-related symptoms, particularly those associated with PMS. However, the evidence is not strong enough to recommend it as a primary treatment for general ovarian health or for all ovarian disorders. More high-quality studies are needed to clarify its broader benefits for the ovaries.

More about vitamin B6
More about Ovaries

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