Evidence supporting the use of: Chastetree
For the body system: Ovaries

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Chastetree (Vitex agnus-castus), also known as chasteberry, has a long history of traditional use for supporting women’s reproductive health, particularly in regulating menstrual cycles and addressing symptoms associated with premenstrual syndrome (PMS) and mild hormone imbalances. Recent scientific studies provide moderate support for its use in supporting the ovaries and overall female reproductive health. Chastetree appears to act primarily by influencing the pituitary gland, resulting in modulation of luteinizing hormone (LH) and prolactin levels. Clinical trials have demonstrated that extracts of Vitex agnus-castus can alleviate symptoms of PMS and cyclical mastalgia, and there is some evidence for its benefit in mild hyperprolactinemia, which can affect ovulation. While direct evidence specifically focused on ovarian health is limited, improvements in menstrual regularity and reduction in PMS symptoms suggest a supportive effect on ovarian function. The European Medicines Agency and several systematic reviews acknowledge its efficacy for certain gynecological complaints, though they note that more high-quality, large-scale studies are needed. Overall, the scientific evidence for Chastetree supporting the ovaries is moderate, predominantly through its effect on hormonal regulation rather than direct action on ovarian tissue.

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