Evidence supporting the use of: Flavanol (mixture)
For the health condition: Osteoporosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flavanols, a subclass of flavonoids found in foods such as cocoa, tea, apples, and berries, have been investigated for their potential role in supporting bone health and possibly preventing or treating osteoporosis. Scientific interest in flavanols for osteoporosis arises from their antioxidant and anti-inflammatory properties, which are believed to influence bone remodeling processes. Preclinical studies (animal and in vitro) suggest that flavanols may promote osteoblast (bone-forming cell) activity and inhibit osteoclast (bone-resorbing cell) activity, thereby favoring bone formation over bone loss.

Some small human clinical trials and observational studies have reported associations between higher flavanol intake and improved markers of bone health, such as increased bone mineral density (BMD) or reduced bone turnover markers. For example, certain trials using cocoa flavanols or green tea extracts have shown modest benefits on bone biomarkers in postmenopausal women, a population at risk for osteoporosis. However, these studies tend to be short-term, have small sample sizes, and often use surrogate endpoints rather than clinical outcomes like fracture risk.

Overall, while there is a scientific rationale and some preliminary evidence that flavanol mixtures could be beneficial for bone health, the quality and quantity of evidence remain limited. Larger, longer-term randomized controlled trials are needed to establish efficacy and clinical relevance in osteoporosis treatment or prevention.

More about Flavanol (mixture)
More about Osteoporosis

Other ingredients used for Osteoporosis

7-hydroxymatairesinol (HMR)
Alfalfa
algal oil
alpha-ketoglutarate (AKG)
anthocyanins
ashwagandha
astragalus
beta caryophyllene
sesame
blueberry
boron
bovine
broccoli
calcium
catechins
caterpillar mushroom
cissus quadrangularis
collagen
collard
conjugated linoleic acid (CLA)
curcumin
DHEA (dehydroepiandrosterone)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish protein
genistein
genistin
glycitin
gooseberry
hesperetin
hesperidin
horsetail
ipriflavone
knotweed
kale
lentinula edodes mycelia
lignans
maca
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
olive
omega-3 fatty acids
phosphorus
pomegranate
prune
quercetin
rehmannia glutinosa
resveratrol
rutin
sardines
silicon
soybean
specialized pro-resolving mediators (SPMs)
strontium
tocotrienols
tomato
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
whey protein
zinc
red clover
haliotis
cistanche
dioscorea
fern
royal jelly
Equol (proprietary)
barrenwort
goji berry
AMP-activated protein kinase (AMPK)
soy isoflavones
8-Prenylnaringenin
Animal Tissue
Antler
Apigenin
Algas calcareas
Acacetin
Astragaloside
Ampelopsin
Algal protein
Algalin
Abalone
Arctiin
Astragalin
Animal protein
Bok Choy
Bovine Protein
biochanin
Bone Protein
Calycosin
Cod Liver Oil
Cyanidin
Chinese Ligustrum berry
DHEA
Daidzein
Diosgenin
Drynaria
Diosmetin
epicatechin
Ecdysteroids
Eicosapentaenoic Acid
Eucommia ulmoides
Estrogen
Fo-Ti
formononetin
Fish
Flavanones
Flavans
Flavanols
Flavones
Hyperoside
Isoflavones
icariin
Kaempferol
Lycium
Lithothamnion
Legume protein
Mineral Blend
Marine Protein
Milk Protein
Naringenin
Neoeriocitrin
Puerarin
Phytoecdysteroid
Phaeophyceae
Polysaccharides
Procyanidin
Proanthocyanidins
Polyunsaturated Fat
Paeoniflorin
Phytoestrogens
Polymethoxylated flavones
Rehmannia
Soy
Soy Protein
silica
Shilajit
Stilbenoid
Ursolic Acid
Vegetable Protein
Wakame
Xanthophyll

Products containing Flavanol (mixture)

We currently have no products on Caring Sunshine that contain this ingredient.