Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rehmannia glutinosa (commonly referred to as "Rhemannia" or "Shu Di Huang" in Chinese medicine) has a long-standing history of use in Traditional Chinese Medicine (TCM) for supporting kidney health, including conditions such as nephritis (inflammation of the kidneys). In TCM, Rehmannia is considered a key herb for nourishing the "Yin" of the kidneys, believed to help with symptoms like fatigue, dizziness, and urinary abnormalities associated with kidney weakness or inflammation.

However, the evidence supporting Rehmannia’s use in nephritis is primarily based on traditional usage rather than robust scientific validation. A small number of laboratory and animal studies suggest that Rehmannia extracts may have anti-inflammatory and immunomodulatory effects that could theoretically benefit kidney inflammation. For example, some animal models have shown improvements in renal function and histopathology with Rehmannia administration. Despite these findings, high-quality clinical trials in humans are lacking, and no formal recommendations exist in Western medicine for its use in nephritis.

In summary, Rehmannia’s use for nephritis is justified mainly by traditional practice in TCM, with only preliminary scientific support. The evidence is limited and does not yet meet the standards required for confirmation of efficacy and safety in the treatment of nephritis.

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