Evidence supporting the use of: Cannabinoids
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Cannabinoids, particularly delta-9-tetrahydrocannabinol (THC) and nabilone, have scientific validation for the treatment of nausea and vomiting, especially when related to chemotherapy. Numerous clinical trials and systematic reviews have demonstrated that cannabinoids are effective in reducing chemotherapy-induced nausea and vomiting (CINV) in patients who do not respond to conventional antiemetics. Both dronabinol (synthetic THC) and nabilone are approved by regulatory agencies such as the U.S. FDA for this specific indication. The mechanism behind their antiemetic effect is thought to involve the activation of cannabinoid receptors (CB1) in the central nervous system, which modulates the vomiting reflex. Early research in the 1970s and 1980s established the efficacy of cannabinoids compared to placebo and, in some cases, compared to older antiemetic agents. More recent meta-analyses confirm that cannabinoids are moderately effective, though their use may be limited by side effects such as dizziness, dysphoria, and sedation. There is less robust evidence for use in other types of nausea, such as that associated with pregnancy or gastrointestinal disorders, and cannabinoids are not generally recommended in those settings. Overall, the scientific evidence is strongest for refractory CINV, justifying a high evidence rating for this particular use.

More about Cannabinoids
More about Nausea and Vomiting

Other ingredients used for Nausea and Vomiting

Allspice
bamboo
Myrobalan
benegut perilla (proprietary)
betel
black pepper
chamomile
chen pi
Coptis chinensis
fennel
fenugreek
ginger
gooseberry
jujube
kudzu
licorice root
lovage
Mint
orange
Peppermint
phytocannabinoids
sage
spearmint leaf
vitamin B6
Watermelon
chickweed
tangerine
typhonium
hyssop
cardamom
atractylodes
alpinia galangal
Hedychium spicatum
anise
Swertia
Szechuan lovage
prickly ash
root tuber
chrysanthemum
flowering quince
dogwood
dioscorea
sweetgums
caraway
camphor oil
Yerba mate
peach
horehound
Sichuan pepper
soursop
sea salt
apple cider vinegar
Agastache
Amomum
Asarum heterotropoides
asafoetida
Agarwood
Asam gelugor
Angostura
arrowroot
Agrimonia pilosa
Amor seco
Asarum sieboldii
atractylone
black seed
buttermilk
blue flag
Bryonia
bai ji
balsam
bael
butternut
Baccharoides anthelmintica
banyan
black salt
back nightshade
Buddha\'s hand
Borassus aethiopum
bitter principals
banana
Black Hellebore
balloon flower
bottle gourd
cumin
centaury
Camellia sinensis
Chinese silkvine
Clerodendrum trichotomum
coriander
cinquefoil
Cyathula
citron
carvone
Cymbopogon martini
coca
cubeb
chirata
cannabidiol
calamus
colocynth
cola nut
dill
Doxylamine succinate
Evodia
English horsemint
elephant\'s head
Embelia
fernbush
false calumba
goldthread
gentian
Gentianella alborosea
Gentianopsis barbata
giant blazingstar
Homalomena
Indian ipecac
Javanese Long Pepper
Kukicha
kola nut
loquat
lime
Large-leaf gentian
Lesser speargrass
linden
lotus
Large-leaved linden
little ironweed
Mentha haplocalyx
mandarin
Marjoram
Marsh Tea
mace
Malva sylvestris
Matapalo Tree
Meadowsweet
Nardostachys
Natsudaidai
Ophiopogon
Osmanthus
Phragmites
Piper chaba
Pulsatilla
Pepper Bark Tree
Phthalides
Piper retrofractum
Polygonatum
Pimpinella
Persimmon
Plectranthus amboinicus
quince
rue
Rubus
Rubiaceae
rose
Rhus coriaria
Stephania root
Sensitive Plant
Southernwood
Savory
Scabrous Gentian
Sweet Bay
Sassafras
Sweet Orange alcohol
Tarragon
Vervain
Vanilla
Yuzu
Yellow Nut Sedge

Products containing Cannabinoids

We currently have no products on Caring Sunshine that contain this ingredient.