Evidence supporting the use of: Black Nightshade
For the health condition: Nausea and Vomiting

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Black Nightshade (Solanum nigrum) has a long history of use in various traditional medicine systems, including Ayurveda, Traditional Chinese Medicine, and folk medicine in Africa and Europe. In these traditions, different parts of the plant—such as the leaves, berries, and roots—have been used for a range of ailments, including digestive complaints like nausea and vomiting. The rationale for its use generally stems from its reputed anti-inflammatory and calming effects on the gastrointestinal tract. However, the scientific evidence supporting these traditional uses is extremely limited. There are only a few preclinical studies that have explored the plant’s phytochemistry, showing the presence of glycoalkaloids, flavonoids, and saponins, but none have directly addressed its efficacy for nausea or vomiting in humans.

Moreover, Black Nightshade contains toxic compounds (notably solanine and related alkaloids), which can be harmful or even fatal in high doses. No high-quality clinical trials exist that validate its safety or efficacy for treating nausea or vomiting. Therefore, while its use for these symptoms persists in some traditional contexts, this is not supported by robust scientific evidence, and safety concerns further limit its practical application for this purpose.

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