Evidence supporting the use of: Sulfur compounds (unspecified)
For the body system: Nails

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Sulfur compounds, particularly in the form of methylsulfonylmethane (MSM) and cysteine (a sulfur-containing amino acid), have some scientific basis for supporting nail health. Sulfur is a key component of keratin, the structural protein that forms nails, hair, and skin. Clinical studies have shown that supplementation with MSM can improve nail strength and reduce brittleness, although the quality of evidence varies and more robust, large-scale trials are needed. Cysteine, as part of dietary protein or supplements, is also important for keratin synthesis. Historically, sulfur-rich foods and compounds have been associated with strong nails in traditional health practices, but in recent decades, scientific research has begun to elucidate the biochemical role of sulfur in keratinization and nail growth. Nevertheless, the evidence is not overwhelming, and while sulfur appears to play a supportive role in nail health by contributing to keratin structure, it is not considered a primary treatment for nail disorders. Most of the positive findings come from small studies or anecdotal reports, so the evidence is moderate but not definitive.

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