Evidence supporting the use of: Amino Acid (unspecified)
For the body system: Nails

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Amino acids are the building blocks of proteins, which are essential for the structure and health of nails. Keratin, the primary protein in nails, is synthesized from various amino acids, including cysteine, methionine, and others. Scientific studies have established that protein and amino acid deficiencies can lead to brittle or unhealthy nails. However, supplementation with "unspecified" amino acids (as opposed to targeted supplementation with specific ones like cysteine or biotin) has limited direct evidence in improving nail health in otherwise healthy individuals.

Most scientific validation comes from understanding the biology of nail formation and case reports of nail changes in severe malnutrition or protein deficiency. There is some evidence from clinical studies that protein-rich diets, or supplementation in cases of deficiency, can improve nail strength and growth. However, there are few high-quality, placebo-controlled trials specifically examining the impact of non-specific amino acid supplementation on nail health.

In summary, while the biological rationale is strong, and there is indirect scientific evidence supporting the role of amino acids in nail health, the direct evidence for supplementation with “unspecified” amino acids in people without dietary deficiencies is moderate. Thus, the use of amino acids to support the nail body system is scientifically plausible, but the strength of the evidence is rated as moderate (3 out of 5).

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