Evidence supporting the use of: Vitamin B1 (thiamin disulfide)
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Vitamin B1, also known as thiamin (not thiamin disulfide, which is a synthetic form sometimes used for increased stability), is an essential water-soluble vitamin that plays a critical role in energy metabolism, particularly in the conversion of carbohydrates into energy. Thiamin serves as a coenzyme (thiamin pyrophosphate) for several enzymes involved in the Krebs cycle and the pentose phosphate pathway, which are fundamental biochemical processes for energy production in all cells, including muscle tissue.
Deficiency of thiamin can lead to muscle weakness, fatigue, and, in severe cases, the disease beriberi, which is characterized by profound muscular and neurological symptoms. While thiamin supplementation is clearly beneficial in reversing deficiency states and the associated muscle symptoms, there is limited evidence that supplemental thiamin enhances muscle function in healthy, non-deficient individuals. Most clinical and experimental studies focus on preventing and treating deficiency rather than enhancing athletic performance or muscle health in the general population.
In summary, the use of vitamin B1 to support the muscle system is scientifically validated in cases of deficiency, where it is necessary for optimal muscle function. However, there is little evidence to support its use for muscle health in individuals with adequate thiamin status. The evidence rating reflects its essential role in deficiency, but lack of strong evidence for benefit beyond correcting deficiency.
More about Vitamin B1 (thiamin disulfide)
More about Muscles
Other ingredients that support Muscles
acetyl l-carnitineadenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
astaxanthin
beet
beta-alanine
bovine
bovine liver
branched-chain amino acids
bromelain
caffeine
calcium
cherry
chloride
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
turmeric
d-alpha tocopherol
devil's claw
dong quai root
fish protein
forskohlii root
l-isoleucine
iron
kale
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-carnosine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-proline
l-taurine
l-threonine
l-valine
magnesium
malic acid
maltodextrin
maltose
methylsulfonylmethane (MSM)
milk
nicotinamide riboside
ornithine alpha-ketoglutarate
peppermint oil
phosphorus
phytocannabinoids
potassium
protein
quinoa
rhizome
sardines
black ginger
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
tongkat ali
ubiquinol
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin D3
water
watermelon
whey protein
white willow
β-nicotinamide mononucleotide (NMN)
suma
squawvine
sodium salt
solomon's seal
siler root
eucommia
electrolytes blend (proprietary)
guelder rose
polyphenols
trace minerals
wintergreen
camphor oil
menthol oil
wheat germ
wood betony
herbal blend (proprietary)
algae
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
arnica
17 alpha methyl 17 beta hydroxy 5 alpha androst 2 ene
17a-di methyl-bol
11-Ketotestosterone
2, 17a-dimethyl-17b-hydroxy-5a-androstan-1-ene-3-one
2a, 17a-dimethyl-17b-hydroxy-5a-androstan-3-one
Arginine Alpha Ketoglutarate
Animal Tissue
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Avocado
Anserina
Alpha-ketoisocaproic acid
Acetylcholine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine alpha-ketoisocaproate
Arginine silicate
Animal protein
Blue Cohosh
Biopeptide
Beta-hydroxybutyrate
Bicarbonate
Beef Protein
Black galingale
Beef
Beef liver
Bovine Protein
Black Gram
Black willow
Ba Ji Tian
Bee products
banana
BCAA
Chia seed
Casein
Cardarine
Chinese Mountain Ant
Carnosine
Citrate malate
Cyathula
Curcuminoid
Cramp Bark
Chuchuhuasi
Cyanotis Vaga
Coca
Coconut Water
Cetylated Fatty Acids
Creatine
Chicken
Curcuma
C-Phycocyanin
Cyanotis arachnoides
DL-Methionine
Deer Velvet
Date
D-Ribose
Dextrose
Dimethyl sulfoxide (DMSO)
Dipsacus
Dipeptide
epicatechin
Epistane
Egg
Erythrina
Elk antler
Eurycoma Longifolia
Emu Oil
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Essential Oil Blend
Egg protein
Fish
Fatty acids
fibroblast growth factor
Ginsenosides
Glutamine
GMS-ribose
glucose
Glycocyamine
Glycerol
Glycine
Isoleucine
Milk Protein
Phosphate Salt
Potash
Quinoa Protein
Shellfish
salt
Soy Protein
Tribulus Terrestris
Other body systems supported by Vitamin B1 (thiamin disulfide)
BrainCirculatory System
Digestive System
Gastrointestinal Tract
Heart
Mitochondria
Muscles
Nerves
Small Intestines
