Evidence supporting the use of: MSM (Methylsulfonylmethane)
For the body system: Muscles
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Methylsulfonylmethane (MSM) is a sulfur-containing compound commonly found in dietary supplements marketed for joint and muscle health. Scientific interest in MSM has grown due to its purported anti-inflammatory and antioxidant properties. Several clinical studies have investigated MSM’s effects on muscle recovery and soreness, particularly following intense exercise. For example, a randomized, double-blind, placebo-controlled study published in the Journal of Sports Medicine and Physical Fitness (2012) found that MSM supplementation (3 g/day for 28 days) reduced muscle soreness and fatigue following running, compared to placebo. Another study in Journal of the International Society of Sports Nutrition (2015) reported that MSM supplementation reduced exercise-induced muscle damage and oxidative stress markers in healthy men. However, the body of evidence supporting MSM for muscle health is still relatively limited, with most studies being small in size and of short duration. While results are promising and suggest that MSM may help reduce muscle soreness and improve recovery, more large-scale, well-designed clinical trials are needed to fully validate its efficacy. Overall, MSM is used to support the muscle system based on a growing, albeit not yet robust, body of scientific research rather than solely on traditional use.
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acetyl l-carnitineadenosine 5-triphosphate disodium (ATP)
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
astaxanthin
beet
beta-alanine
bovine
bovine liver
branched-chain amino acids
bromelain
caffeine
calcium
cherry
chloride
coenzyme Q10 (CoQ10)
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
turmeric
d-alpha tocopherol
devil's claw
dong quai root
fish protein
forskohlii root
l-isoleucine
iron
kale
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-carnosine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-proline
l-taurine
l-threonine
l-valine
magnesium
malic acid
maltodextrin
maltose
methylsulfonylmethane (MSM)
milk
nicotinamide riboside
ornithine alpha-ketoglutarate
peppermint oil
phosphorus
phytocannabinoids
potassium
protein
quinoa
rhizome
sardines
black ginger
soybean
specialized pro-resolving mediators (SPMs)
spinach
spirulina
tongkat ali
ubiquinol
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin D3
water
watermelon
whey protein
white willow
β-nicotinamide mononucleotide (NMN)
suma
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solomon's seal
siler root
eucommia
electrolytes blend (proprietary)
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trace minerals
wintergreen
camphor oil
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wheat germ
wood betony
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Arachidonic Acid
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Avocado
Anserina
Alpha-ketoisocaproic acid
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adenosine triphosphate (ATP)
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Alpha hydroxyisocaproic acid
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Animal protein
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Biopeptide
Beta-hydroxybutyrate
Bicarbonate
Beef Protein
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Bovine Protein
Black Gram
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banana
BCAA
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Cardarine
Chinese Mountain Ant
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Citrate malate
Cyathula
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Cramp Bark
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Cetylated Fatty Acids
Creatine
Chicken
Curcuma
C-Phycocyanin
Cyanotis arachnoides
DL-Methionine
Deer Velvet
Date
D-Ribose
Dextrose
Dimethyl sulfoxide (DMSO)
Dipsacus
Dipeptide
epicatechin
Epistane
Egg
Erythrina
Elk antler
Eurycoma Longifolia
Emu Oil
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Essential Oil Blend
Egg protein
Fish
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fibroblast growth factor
Guanidinoacetic acid
Ginsenosides
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GMS-ribose
glucose
Glycocyamine
Glycerol
Glycine
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Isoleucine
Milk Protein
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Potash
Quinoa Protein
Shellfish
salt
Soy Protein
Tribulus Terrestris
