Evidence supporting the use of: Magnesium citrate malate
For the body system: Muscles

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Magnesium citrate malate is a highly bioavailable form of magnesium, which is an essential mineral involved in many physiological processes, including muscle function. Scientific validation for magnesium’s role in supporting the muscular system is robust. Magnesium acts as a cofactor for enzymes involved in energy (ATP) production and is critical for muscle contraction and relaxation. Deficiency in magnesium is associated with muscle cramps, spasms, and, in severe cases, tetany. Several clinical trials and observational studies have shown that magnesium supplementation can reduce the incidence and severity of muscle cramps, particularly in populations prone to deficiency (such as older adults, athletes, and pregnant women). For example, a 2012 randomized controlled trial found that magnesium supplementation reduced the frequency of nocturnal leg cramps in pregnant women. Magnesium citrate malate is particularly well-absorbed compared to other forms, which may enhance its efficacy for muscle support. However, while evidence supports magnesium supplementation for those with low magnesium status, its benefits for muscle health in individuals with adequate intake are less clear. Overall, the use of magnesium citrate malate to support muscle health is strongly grounded in scientific evidence, particularly for preventing and alleviating muscle cramps due to deficiency.

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Products containing Magnesium citrate malate

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