Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glycine propionyl-L-carnitine (GPLC) is a derivative of L-carnitine that has been studied primarily for its potential to enhance exercise performance and support muscle function. L-carnitine itself is well-known for its role in fatty acid transport into mitochondria, which is crucial for energy production, particularly during physical activity. GPLC is believed to offer additional benefits due to its glycine component, which may have antioxidant and vasodilatory effects.

Some scientific studies have investigated GPLC’s effects on exercise performance and muscle health. Small-scale human trials have suggested that supplementation with GPLC can increase nitric oxide levels, potentially improving blood flow to muscles during exercise. This may aid in reducing muscle fatigue and supporting recovery. Furthermore, limited evidence indicates GPLC may reduce markers of oxidative stress following intense physical activity.

However, the overall body of evidence remains modest, with some studies showing minimal or no benefit. Most research has involved small participant groups and short durations, limiting the generalizability of findings. There is currently insufficient high-quality, large-scale clinical evidence to confidently recommend GPLC for broad muscle support or performance enhancement. While its use is grounded in plausible biological mechanisms and some early positive results, more robust research is needed to fully validate its efficacy for the muscles body system.

More about Glycine propionyl-l-carnitine
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alpha-ketoglutarate (AKG)
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Other body systems supported by Glycine propionyl-l-carnitine

Arteries
Blood
Circulatory System
Heart
Mitochondria
Muscles

Products containing Glycine propionyl-l-carnitine

We currently have no products on Caring Sunshine that contain this ingredient.