Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coleus forskohlii, commonly known as forskohlii root, contains the active compound forskolin. Forskolin has been studied for its effects on body composition and muscle support, with some evidence suggesting it may help promote lean body mass. The proposed mechanism involves forskolin increasing cyclic AMP (cAMP) levels in cells, which could potentially stimulate fat breakdown and influence muscle metabolism. A few small clinical trials have examined forskolin supplementation in overweight and obese individuals. For example, one 12-week study in overweight men found that forskolin supplementation resulted in a significant decrease in body fat percentage and fat mass compared to placebo, and a trend toward increased lean body mass. Another trial in women did not find significant effects on body composition. The number and size of studies are limited, and results have been mixed, so evidence for forskohlii root supporting muscle mass is modest at best. There is also a lack of studies directly assessing its effect on muscle strength or performance. In summary, forskohlii root has some preliminary scientific evidence suggesting a possible benefit for lean mass, but the quality and quantity of evidence do not support strong claims. More rigorous, large-scale trials are needed to confirm its effects on muscle health.

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