Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Hydrastine is a major alkaloid found in the plant Hydrastis canadensis (goldenseal), which has a long history of traditional use in North American herbal medicine. Native American tribes and later, European settlers, utilized goldenseal preparations primarily for their purported effects on mucous membranes of the respiratory, digestive, and genitourinary tracts. Hydrastine, along with berberine, is believed to contribute to these effects, which include reducing inflammation, fighting infections, and supporting the healing of mucosal tissues.

Despite these traditional uses, scientific evidence validating hydrastine’s efficacy for supporting mucous membranes is limited. Most modern research focuses on berberine, another goldenseal alkaloid, with hydrastine much less studied. Some in vitro and animal studies suggest that hydrastine may have mild antimicrobial and astringent properties, but robust clinical trials in humans are lacking. The use of hydrastine for mucous membrane support remains primarily rooted in traditional herbal practice rather than scientific validation. Therefore, while there is a historical precedent for using hydrastine in this context, the quality and quantity of scientific evidence supporting its effectiveness are low.

More about hydrastine
More about Mucus Membranes

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Other body systems supported by hydrastine

Digestive System
Gastrointestinal Tract
Mucus Membranes
Sinuses

Products containing hydrastine

We currently have no products on Caring Sunshine that contain this ingredient.