Evidence supporting the use of: L-tyrosine
For the health condition: Mood Swings

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-tyrosine is an amino acid that serves as a precursor to several important neurotransmitters, including dopamine, norepinephrine, and epinephrine. These neurotransmitters play significant roles in regulating mood, cognitive function, and stress response. The rationale for using L-tyrosine to support or treat mood swings is based on its role in neurotransmitter synthesis. Some scientific studies suggest that L-tyrosine supplementation may help support cognitive performance and mood, particularly in situations of acute stress or sleep deprivation, where neurotransmitter stores can be depleted. However, the evidence specifically linking L-tyrosine supplementation to the treatment or stabilization of mood swings—such as those seen in bipolar disorder or premenstrual syndrome—is limited and not robust.

Most research has focused on L-tyrosine’s effect on cognitive performance and stress resilience, rather than on direct mood stabilization. While a few small studies and case reports hint at possible benefits for mood, larger, well-controlled clinical trials are lacking. As such, while there is a plausible biological mechanism and some preliminary scientific support, the overall quality and quantity of evidence for L-tyrosine’s effectiveness in treating mood swings is low. Therefore, L-tyrosine is not generally recommended as a primary treatment for mood disorders, and its use for mood swings should be considered experimental and approached with caution.

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