Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E, encompassing both tocopherols and tocotrienols, is a fat-soluble antioxidant that has been investigated for its potential role in supporting mitochondrial health. There is scientific evidence suggesting that Vitamin E can protect mitochondria from oxidative stress by neutralizing free radicals, particularly lipid peroxides, which are damaging byproducts of cellular metabolism. Mitochondria are especially prone to oxidative damage due to their role in energy production and the generation of reactive oxygen species (ROS).

Several in vitro and animal studies have demonstrated that Vitamin E supplementation can improve mitochondrial function by preventing lipid peroxidation within the mitochondrial membrane, thus maintaining membrane integrity and function. Some research in human subjects has also suggested that Vitamin E supplementation may reduce markers of oxidative stress and improve mitochondrial efficiency, particularly in populations under oxidative stress, such as the elderly or individuals with certain metabolic disorders.

However, while the protective antioxidant effects of Vitamin E on mitochondria are scientifically plausible and supported by preclinical evidence, human clinical trials are limited and results have been mixed. The evidence is stronger in cell and animal models than in large-scale human studies. Therefore, the evidence supporting Vitamin E’s role specifically in mitochondrial support is moderate but not conclusive.

More about Vitamin E (mixied tocopherols and tocotrienols)
More about Mitochondria

Other ingredients that support Mitochondria

Other body systems supported by Vitamin E (mixied tocopherols and tocotrienols)

Products containing Vitamin E (mixied tocopherols and tocotrienols)