Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Squaw Vine (Mitchella repens) has a long history of use in traditional herbal medicine, particularly among Native American and early Euro-American herbalists. It was used chiefly as a uterine tonic and to support female reproductive health, including for conditions such as scant menstruation (hypomenorrhea). Historical texts, such as King's American Dispensatory and various Eclectic and Thomsonian materia medicas, describe its use as an emmenagogue (an agent that stimulates or increases menstrual flow) and a normalizing agent for menstrual irregularities. However, these uses are based on traditional knowledge and anecdotal reports rather than rigorous scientific evaluation.

There is little to no scientific research or clinical evidence available to substantiate the efficacy of Squaw Vine for scant menstruation. Modern herbal reference texts may mention its traditional use, but they also often note the lack of controlled studies. The active constituents of Squaw Vine, such as saponins and tannins, have not been specifically linked to hormonal or menstrual effects in scientific literature. As a result, while its use for scant menstruation is well documented in folk and historical herbalism, it is not currently supported by scientific validation. The rating of 1 reflects the existence of a traditional basis, but with minimal supporting evidence from well-designed studies.

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