Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Tree Peony (Paeonia suffruticosa) has a long history of use in traditional Chinese medicine (TCM) for a variety of women's health conditions, including menopause-related symptoms. In TCM, Tree Peony root (often called "Mu Dan Pi") is considered to have properties that "cool the blood" and regulate menstrual function. It is a common ingredient in classic herbal formulas such as "Jia Wei Xiao Yao San," which is prescribed to manage symptoms like irritability, hot flashes, and night sweats during menopause. These uses are based on centuries of empirical practice rather than modern scientific validation.

Scientific research on Tree Peony's direct effect on menopausal symptoms is limited. Some preclinical studies suggest that Tree Peony contains compounds (such as paeoniflorin) which may have anti-inflammatory and neuroprotective effects, and it is sometimes included in combination herbal preparations that have been studied for menopausal symptoms. However, high-quality randomized controlled trials specifically investigating Tree Peony alone for menopause are lacking. Most evidence supporting its use is derived from traditional practice and small-scale or combination studies, rather than robust clinical trials.

In conclusion, the use of Tree Peony for menopause is justified primarily by traditional practice, with limited and indirect scientific evidence available. The overall quality of evidence is modest and warrants further investigation.

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