Evidence supporting the use of: Lycopene
For the body system: Male Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lycopene, a carotenoid found predominantly in tomatoes, has been investigated for its potential benefits to the male reproductive system, particularly in relation to prostate health and male fertility. Several epidemiological studies and clinical trials suggest that higher dietary intake of lycopene is associated with a reduced risk of prostate cancer, one of the most common cancers affecting men. For example, a meta-analysis published in "Prostate Cancer and Prostatic Diseases" (2015) found a modest inverse relationship between lycopene consumption and prostate cancer risk. Additionally, lycopene’s antioxidant properties may help protect sperm from oxidative stress, potentially improving sperm quality, motility, and overall male fertility, as supported by small clinical trials and reviews such as those in "Antioxidants" (2021).

However, the evidence is not entirely consistent. While some randomized controlled trials have shown beneficial effects on semen parameters and markers of oxidative stress, others have not observed significant improvements. Most positive findings involve supplementation with purified lycopene or tomato extracts rather than dietary intake alone. The use of lycopene for broader aspects of male reproductive health beyond prostate and sperm parameters is less well-established, and further large-scale, well-controlled studies are needed to clarify its efficacy. Overall, lycopene is supported by a moderate level of scientific evidence for supporting aspects of the male reproductive system, mainly prostate health and possibly sperm quality.

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