Evidence supporting the use of: American Dogwood
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

American Dogwood (Cornus florida) has a history of traditional use in North American folk medicine, especially among Indigenous populations and early settlers. During the 18th and 19th centuries, the bark of American Dogwood was used as a substitute for quinine to treat fevers, particularly those associated with malaria. This use was largely due to the scarcity of imported quinine from South America and was motivated by the similarity in bitterness between the two barks. However, while there are historical accounts and anecdotal reports of its use for fever and malaria, there is a lack of rigorous scientific evidence or clinical trials to support its efficacy against malaria. Phytochemical studies have shown that the bark contains tannins and other astringent compounds, but it does not contain quinine or related alkaloids known to have antimalarial activity. Therefore, while its use is well-documented in tradition, the scientific support for American Dogwood as an antimalarial remedy is minimal.

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