Evidence supporting the use of: Vitamin E (mixed tocopherols)
For the health condition: Macular Degeneration
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin E (mixed tocopherols) has been studied for its potential role in supporting or treating age-related macular degeneration (AMD), primarily in the context of its antioxidant properties. The most significant evidence comes from the Age-Related Eye Disease Study (AREDS and AREDS2), large, multi-center, randomized clinical trials funded by the National Eye Institute. In these studies, vitamin E was included as part of a specific antioxidant supplement formula (along with vitamin C, beta-carotene or lutein/zeaxanthin, zinc, and copper) that was shown to reduce the risk of progression to advanced AMD in individuals with intermediate or advanced disease in one eye. However, when examined independently, vitamin E alone has not demonstrated significant benefits in preventing or slowing AMD progression. Other studies and meta-analyses have similarly found little to no effect for vitamin E supplementation by itself on AMD risk or progression. Thus, the use of vitamin E for AMD is justified by its inclusion in a validated multi-nutrient formula, but not as a stand-alone treatment. Current clinical guidelines do not recommend vitamin E alone for AMD prevention or treatment, though it may play a supportive role as part of the AREDS/AREDS2 supplement regimen.
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Other ingredients used for Macular Degeneration
algal oilalpha-carotene
anchovies
anthocyanins
astaxanthin
beta-carotene
blueberry
cryptoxanthin
turmeric
d-alpha tocopherol
DHA (docosahexaeonic acid)
fish oil
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lutein
marine lipid
mixed carotenoids
omega-3 fatty acids
vitamin A
vitamin C
vitamin E
zeaxanthin
zinc
algae
3,3'-dihydroxy-B-carotene-4,4'-dione
Avocado
anthocyanidins
Bioflavonoids
Cyanidin
Docosahexaenoic Acid
Eicosapentaenoic Acid
Other health conditions supported by Vitamin E (mixed tocopherols)
Age SpotsAging (prevention)
Alzheimer's Disease
Arteriosclerosis
Arthritis
Asthma
Breast Lumps
Bruises (healing)
Bruises (prevention)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cuts
Dementia
Dermatitis
Diabetic Retinopathy
Eye Problems
Fatty Liver Disease
Free Radical Damage
Hepatitis
Inflammation
Inflammatory Bowel Disorders
Macular Degeneration