Evidence supporting the use of: Polyphenols (npt specified)
For the body system: Lymphatics

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Polyphenols, a diverse group of naturally occurring compounds found in plants, have been investigated for their wide-ranging health benefits, particularly for cardiovascular and metabolic health. Scientific evidence directly supporting their use for the lymphatic system, specifically, is limited but emerging. The lymphatic system is crucial for immune function and fluid balance, and some studies have explored how polyphenols may influence inflammation, immune modulation, and vascular permeability, which are indirectly related to lymphatic health. For example, flavonoids—a major class of polyphenols—have demonstrated anti-inflammatory and antioxidant effects that could theoretically benefit lymphatic vessel function or reduce lymphedema, as suggested by small-scale studies and animal models. Certain polyphenols, such as those found in green tea (epigallocatechin gallate) and citrus fruits (hesperidin), have been shown to strengthen capillary walls and reduce edema in some clinical contexts. However, robust, large-scale clinical trials specifically targeting lymphatic disorders are lacking. Overall, while there is some scientific rationale and preliminary evidence for polyphenols supporting lymphatic health, especially via their anti-inflammatory and vascular-protective effects, conclusive evidence is insufficient. Thus, the use of polyphenols for lymphatic support is rated as modestly supported by science at this time.

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