Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Blepharis, a genus of plants in the family Acanthaceae, has been used in various traditional medicine systems, including Ayurveda and African folk medicine. The traditional use of Blepharis species (notably Blepharis edulis and Blepharis maderaspatensis) has included support for general detoxification and treatment of ailments such as fever, cough, and urinary disorders. Some ethnobotanical reports mention its use for conditions that may involve the liver, such as jaundice, but documentation is sparse and often anecdotal. There is a lack of robust clinical or preclinical scientific studies specifically evaluating Blepharis for liver detoxification or hepatoprotective effects. Most available evidence is based on traditional knowledge rather than scientific validation. Consequently, while Blepharis may appear in some herbal formulas for "liver detox," its use for this purpose is rooted primarily in tradition, with minimal direct evidence supporting efficacy or mechanism of action. No major pharmacological studies or clinical trials have established its safety or effectiveness in liver detoxification. Therefore, its use should be considered with caution and not as a substitute for evidence-based therapies.

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