Cape Aloe (Aloe ferox) is traditionally and scientifically recognized for its use as a stimulant laxative to support the large intestine (colon). The primary active constituents are anthraquinone glycosides, such as aloin, which have been shown to increase intestinal water content, stimulate peristalsis, and promote bowel movements. This mechanism is well documented in pharmacological studies and underpins the use of Cape Aloe in over-the-counter laxative products.

Clinical trials and systematic reviews have demonstrated that anthraquinone-containing preparations, including those from Cape Aloe, are effective for short-term relief of constipation. However, these compounds must be used with caution, as prolonged or excessive use can lead to electrolyte imbalances, dehydration, and dependency. Regulatory agencies, including the U.S. FDA and EMA, acknowledge the efficacy of such stimulant laxatives but warn against chronic use due to potential adverse effects.

In summary, both traditional use and modern pharmacological evidence support the role of Cape Aloe in promoting bowel movements and alleviating constipation by acting directly on the colon. However, its use is recommended for short-term relief only, and individuals should be aware of possible side effects with long-term or high-dose use.