Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Aloe, particularly Aloe vera, has a long history of use in traditional medicine systems for supporting the large intestines and promoting bowel regularity. The latex portion of the aloe leaf, which contains compounds called anthraquinones (mainly aloin), has been used as a stimulant laxative to treat constipation. Historical texts from ancient Egypt, Greece, and Rome mention the use of aloe for its purgative effects. In traditional herbal medicine, aloe preparations were commonly recommended for short-term relief of constipation because of their ability to stimulate bowel movements by increasing intestinal water content and peristalsis.

However, modern clinical research on aloe's effectiveness and safety as a laxative is limited. While the laxative effect of aloe latex is well-established and recognized by regulatory agencies (such as the FDA and EMA), concerns over potential toxicity, dependency, and carcinogenicity have led to restrictions on its use in over-the-counter products. The gel portion of Aloe vera (the clear inner pulp) is not a laxative and is sometimes used for soothing purposes, but evidence for its benefit in colon health is lacking. Overall, aloe's use for large intestine support is primarily traditional, with some pharmacological basis but limited high-quality clinical validation, and significant safety concerns limit its modern use.

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