Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacillus subtilis is a spore-forming probiotic bacterium that has been studied for its potential to support digestive health, including lactose intolerance. The scientific rationale for its use in lactose intolerance stems from its capacity to produce various enzymes, including β-galactosidase (lactase), which can aid in the breakdown of lactose in the digestive tract. Some in vitro studies and animal models have demonstrated that certain strains of B. subtilis are capable of secreting lactase, suggesting a mechanism by which they could alleviate symptoms of lactose intolerance by enhancing lactose digestion. However, clinical evidence in humans is limited. Compared to more established probiotics like Lactobacillus acidophilus and Bifidobacterium species, there are few randomized controlled trials directly assessing the efficacy of B. subtilis in improving lactose tolerance or reducing symptoms such as bloating, diarrhea, and abdominal pain in lactose-intolerant individuals. The available human studies are small and often use multi-strain probiotic formulations, making it difficult to isolate the specific contribution of B. subtilis. In summary, while there is a plausible scientific mechanism and some preliminary evidence, the overall quality and quantity of clinical data supporting B. subtilis as a treatment for lactose intolerance are currently limited. Therefore, its use is justified by emerging scientific understanding rather than strong clinical validation, meriting a moderate evidence score.

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Nature's Sunshine AIVIA Performance Probiotic