Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cissus quadrangularis is a plant traditionally used in Ayurvedic medicine for bone health and joint support. Recent scientific studies have begun to validate some of these traditional uses. Research has shown that extracts of Cissus quadrangularis may have anti-inflammatory, analgesic, and antioxidant properties, which could account for its supportive effects on the joints. Several animal studies and a few small human trials have indicated that Cissus quadrangularis supplementation can help reduce joint pain and improve mobility, particularly in conditions like osteoarthritis and exercise-induced joint damage.

One randomized controlled trial (Oben et al., 2006) reported that participants receiving Cissus quadrangularis extract experienced reduced joint pain and improved function compared to placebo. Other studies have demonstrated its potential to promote bone healing and decrease markers of inflammation. However, while these findings are promising, the body of evidence remains limited by small sample sizes, short durations, and methodological issues. Larger and more rigorous clinical trials are needed to confirm efficacy and safety.

In summary, while Cissus quadrangularis is rooted in traditional medicine, there is emerging scientific evidence supporting its use for joint health, justifying a moderate evidence rating. Caution should still be exercised until more robust data are available.

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