Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Scrophularia root (commonly known as "Xuan Shen" in Traditional Chinese Medicine) has a long history of use in East Asian herbal medicine, particularly for conditions described as "heat" or "toxic heat" in the body, which are sometimes associated with jaundice. In TCM theory, jaundice can arise from "damp-heat" in the liver and gallbladder, and herbs like scrophularia root are used to "clear heat," "cool the blood," and "detoxify." Historical texts from Chinese herbalism list Xuan Shen as one of several herbs prescribed in formulations for jaundice and related liver conditions. However, there is minimal scientific evidence from modern clinical trials or pharmacological studies to support its efficacy specifically for adult jaundice. Most published research on scrophularia root focuses on its anti-inflammatory and immunomodulatory effects in vitro or in animal models, not on jaundice in humans. No high-quality randomized controlled trials have confirmed its benefit in treating jaundice, and it is not recognized in Western medicine as an effective treatment for this condition. Therefore, its use for jaundice is best categorized as traditional, with the evidence for efficacy being weak and primarily based on historical and anecdotal accounts rather than rigorous scientific validation.

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