Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Macaranga indica has been traditionally used in various parts of India for the management of jaundice, particularly in adult populations. Ethnobotanical surveys and local medicinal practices document the use of Macaranga indica leaves and bark in herbal preparations administered to individuals with symptoms of jaundice. For instance, studies such as those published in the Journal of Ethnopharmacology (e.g., J. Ethnopharmacol. 2008;118(2):327-39) and regional field reports (notably from Maharashtra and Karnataka) mention its inclusion in polyherbal remedies for liver complaints, including jaundice.

However, the evidence supporting its efficacy is primarily anecdotal and based on longstanding tradition rather than clinical trials or robust pharmacological studies. A few phytochemical screenings of Macaranga indica reveal the presence of flavonoids and other bioactive compounds with potential antioxidant and hepatoprotective properties, but direct studies evaluating its effect in jaundice models or in humans are lacking. Therefore, while its use is well-documented in traditional medicine systems, there is insufficient scientific validation to support its efficacy for jaundice treatment.

In summary, the use of Macaranga indica for jaundice is grounded in traditional knowledge with limited preclinical support, and there is a need for further scientific investigation to confirm its safety and effectiveness for this indication.

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