Evidence supporting the use of: Little ironweed
For the health condition: Jaundice (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Little ironweed (Vernonia cinerea) has a long-standing history of use in traditional medicine systems, particularly in South and Southeast Asia. In Ayurvedic and folk medicine, various parts of the plant are employed to manage liver-related ailments, including jaundice. Traditional healers often prepare decoctions or extracts from the aerial parts or leaves, which are then administered to individuals exhibiting symptoms of jaundice, such as yellowing of the skin and eyes.

The rationale in traditional contexts is based on the plant's purported "liver-protective" and detoxifying properties. However, scientific validation for the use of Vernonia cinerea specifically for jaundice is limited. Some preliminary studies have reported hepatoprotective effects in animal models, with extracts showing the ability to reduce liver enzyme levels and oxidative stress induced by toxins. However, these studies are few, often use small sample sizes, and do not directly study jaundice in humans. Clinical trials or robust pharmacological studies confirming its efficacy and safety in adult jaundice are lacking.

Therefore, the use of Little ironweed for jaundice is primarily justified by traditional knowledge, with only minimal scientific evidence, mostly from preclinical studies. It should be used with caution, and not as a substitute for standard medical care.

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