Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Polyphenols, a diverse group of phytochemicals found in plant-based foods such as fruits, vegetables, tea, and cocoa, have been studied for their potential benefits in managing symptoms of Irritable Bowel Syndrome (IBS). The rationale for their use is based on their anti-inflammatory, antioxidant, and prebiotic effects, which may help modulate gut microbiota and reduce gastrointestinal symptoms. Small-scale clinical studies and animal research suggest that certain polyphenol-rich foods (such as green tea, cocoa, or berries) may improve gut barrier function, decrease inflammation, and alleviate some symptoms of IBS, such as bloating and abdominal pain. However, the evidence is still preliminary. Most studies have investigated specific polyphenols or polyphenol-rich foods rather than “mixed” polyphenol supplements. There is some evidence that polyphenols can influence gut microbiota composition, which is relevant to IBS pathophysiology, but robust, large-scale clinical trials directly assessing mixed polyphenols for IBS treatment are lacking. Therefore, while the use of polyphenols for IBS has a scientific basis, the evidence is limited and cannot yet be considered strong or conclusive.

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