Evidence supporting the use of: Bifidobacterium longum
For the health condition: Irritable Bowel Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium longum is a well-studied probiotic strain that has been investigated for its potential benefits in managing symptoms of Irritable Bowel Syndrome (IBS). Clinical research, including several randomized controlled trials (RCTs), suggests that certain strains of B. longum may help alleviate IBS symptoms such as abdominal pain, bloating, and irregular bowel movements. For example, a 2017 double-blind, placebo-controlled trial published in Gastroenterology found that Bifidobacterium longum NCC3001 significantly improved global IBS symptoms and quality of life compared to placebo in patients with IBS. The proposed mechanisms for these effects include modulation of the gut microbiota, strengthening of the intestinal barrier, and modulation of immune responses and gut-brain signaling.

However, while there is scientific validation for its use, the strength of evidence is moderate (rated 3 out of 5) because not all studies show consistent benefit, and the efficacy may depend on the specific strain used, the formulation, and the IBS subtype (e.g., IBS-D, IBS-C, or mixed). Meta-analyses indicate that B. longum is among the more promising probiotic strains for IBS, but further large-scale, high-quality studies are needed to standardize dosing and identify which patient populations benefit most. Overall, B. longum is considered a scientifically validated, but not universally effective, adjunct for IBS management.

More about bifidobacterium longum
More about Irritable Bowel Syndrome

Other ingredients used for Irritable Bowel Syndrome

2'-Fucosyllactose
akkermansia muciniphila
aloe vera
alpha-galactosidase
alpha-pinene
amino acids
bacillus clausii
bacillus coagulans
bacillus subtilis
benegut perilla (proprietary)
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bilberry
bio ecolian (proprietary)
blackberry
Indian frankincense
butyrate triglyceride
chen pi
chia seed
chlorella
cinnamon
turmeric
curcumin
fennel
flaxseed
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
ginger
green banana
green tea
guar gum
cellulose
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lovage
marshmallow
oat
pectin
peppermint oil
plum fruit
pomegranate
potato starch
butyric acid
psyllium
quercetin
resveratrol
saccharomyces boulardii
slippery elm bark
spearmint leaf
streptococcus thermophilus
tributyrin
vitamin D
xylooligosaccharides
zinc
hyssop
atractylodes
ferula assafoetida
anise
holarrhena antidysenterica
fumaria parviflora
chrysanthemum
senna
white oak
algae
Agastache
Asafoetida
Alexandrian senna
Agrimonia pilosa
Betony
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Boswellic Acid
Bayleaf
Belleric myrobalan
Bran
Boswellia
Bacillus licheniformis
black salt
Bifidobacterium animalis
Bitter principals
Bacteria
Bifidobacteria
Bacillus
Cumin
Coriander
Citron
Cannabidiol
Clerodendrum indicum
Dragonhead
Dichrostachys glomerata
Enterococcus
Enzyme Blend
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Rhubarb