Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Agonandra species, such as Agonandra brasiliensis, have been used in traditional medicine in some regions of Central and South America. Ethnobotanical records indicate that parts of the plant, especially the bark and leaves, have been used in folk remedies for various ailments, including as topical applications for injuries such as wounds, bruises, or inflammation. The primary basis for this use appears to be anecdotal and based on local healing traditions rather than formalized written medical systems. There are references to its application for external injuries due to its purported anti-inflammatory or analgesic properties, but these are largely derived from oral histories and informal ethnobotanical surveys.

However, scientific studies specifically evaluating the efficacy or safety of Agonandra for treating or supporting the healing of injuries are lacking. There is a scarcity of published pharmacological research on the plant’s bioactive compounds in the context of wound healing, tissue regeneration, or anti-inflammatory activity relevant to injuries. Therefore, while its use for injuries is documented in traditional contexts, there is minimal scientific validation, and the evidence base remains weak. This results in a low evidence rating for its use in treating injuries.

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