Evidence supporting the use of: Vitamin D
For the health condition: Inflammatory Bowel Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin D is increasingly recognized for its role in the management of Inflammatory Bowel Disorders (IBD), including Crohn's disease and ulcerative colitis. Multiple observational studies have shown that patients with IBD often have lower serum vitamin D levels compared to healthy controls. Vitamin D is known to modulate both innate and adaptive immune responses, and its deficiency is associated with increased disease activity, higher relapse rates, and a greater risk of complications in IBD patients.

Clinical trials evaluating vitamin D supplementation in IBD have yielded mixed but generally promising results. Some randomized controlled trials (RCTs) have demonstrated that vitamin D supplementation can reduce disease activity scores, improve quality of life, and decrease inflammatory markers in patients with IBD. However, the evidence is not uniformly strong or consistent, and there is ongoing debate about optimal dosing and the degree of benefit. Meta-analyses suggest a potential protective effect of adequate vitamin D levels against IBD development and relapse, but more large-scale, high-quality RCTs are needed to establish definitive recommendations.

Current clinical guidelines acknowledge the importance of monitoring and correcting vitamin D deficiency in IBD patients, primarily to support bone health, but also due to its potential immunomodulatory effects. In summary, while vitamin D is not a standalone treatment for IBD, there is moderate scientific evidence supporting its use as an adjunctive therapy, particularly for patients with documented deficiency.

More about vitamin D
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
7,14-Hydroxy-Docosapentaenoic Acid
Acemannan
Akkermansia muciniphila
Algae
algal oil
Aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
andrographolide
anthocyanidins
anthocyanins
apigenin
apocynin
arabinoxylan
arctiin
astragalin
avocado
Bacillus
bacillus clausii
Bacillus licheniformis
bacillus subtilis
bacteria
barberry
barley
Basidiomycota
bentonite
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bioflavonoids
Boswellia
Boswellic Acid
Brassica
butternut
butyrate triglyceride
butyric acid
cannabidiol
casticin
cat's claw
celandine
chamomile
chirata
cichoric acid
citrus pectin
Coptis chinensis
cruciferous
curcumin
dandelion
DHA (docosahexaenoic acid)
eicosapentaenoic acid
ellagitannin
Enterococcus
EPA (eicosapentaenoic acid)
fiber
fish oil
flavans
flaxseed
Frangula
fructooligosaccharides (FOS)
fucoidan
galactooligosaccharides
Glucosinolates
Glutathione
Glycomacropeptides
Glycosphingolipids
Glycyrrhetinic acid
Humic acid
inulin
isomalto-oligosaccharide
Kaempferol
L-glutamine
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus brevis
Lactobacillus casei
Lactobacillus crispatus
Lactobacillus delbrueckii
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus johnsonii
Lactobacillus kefiranofaciens
Lactobacillus kefiri
Lactobacillus lactis
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus sakei
Lactobacillus salivarius
Lactococcus casei
Lactococcus lactis
Lactococcus rhamnosus
Legume protein
licorice root
luteolin
Marshmallow
Myrosinase
Myrrh
N-acetyl-cysteine (NAC)
N-acetyl-glucosamine
Neoandrographolides
nicotinamide riboside
Oligosaccharides
omega-3 fatty acids
Palmitoylethanolamide (PEA)
Pediococcus acidilactici
Pediococcus pentosaceus
Peppermint
phlorotannins
Piperine
polysaccharides
polyunsaturated fat
proanthocyanidins
probiotics
procyanidin
Propionibacterium freudenreichii
psyllium
punarnava
punicalagins
reishi mushroom
rosmarinic acid
Rubia cordifolia
Saccharomyces boulardii
shiitake mushroom
Slippery Elm
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
Sulfated polysaccharide
Sulforaphane
Swertia
Taraxasterol
Trametes
tributyrin
Tumerone
turmeric
Urolithin A
vitamin C
vitamin D
vitamin D3
Xylanase
xylooligosaccharides
Zinc

Other health conditions supported by vitamin D

Allergies (food)
Alzheimer's Disease
Amenorrhea
Anorexia
Apathy
Arrhythmia
Arthritis
Autism
Autoimmune Disorders
Backache
Birth Defects (prevention)
Body Building
Broken Bones
Calcium Deficiency
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Celiac Disease
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Contagious Diseases
Convalescence
Convulsions
Cramps (menstrual)
Cramps and Spasms
Crohn's Disease
Cystic Breast Disease
Cystic Fibrosis
Dandruff
Debility
Dementia
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Erectile Dysfunction
Estrogen (low)
Fibroids (uterine)
Fibromyalgia Syndrome
Fibrosis
Grave's Disease
Grief and Sadness
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Headache (cluster)
Heart (weakness)
Hypertension
Hypothyroid
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Irritable Bowel Syndrome
Itching
Knees (weak)
Leaky Gut Syndrome
Leprosy
Lesions
Leukemia
Lou Gehrig's Disease
Lupus
Lymphoma
Melanoma
Memory and Brain Function
Menopause
Menstrual Irregularity
Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mood Swings
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
Myasthenia Gravis
Nephritis
Nerve Damage
Nervous Exhaustion
Numbness
Nursing
Obsessive Compulsive Disorder
Oral Surgery
Osteoporosis
Pain (general remedies for)
Pancreatitis
Paralysis
Parkinson's Disease
Peripheral Neuropathy
PMS (general)
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Pneumonia
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prostatitis
Psoriasis
Rheumatoid Arthritis
Schizophrenia
Sciatica
Seasonal Affective Disorder
Senility
Acne
Allergies (respiratory)
Arteriosclerosis
Asthma
Anemia
Cardiovascular Disease
Fatigue
Tuberculosis