Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bupleurum is a traditional Chinese medicinal herb commonly used in formulas such as Xiao Chai Hu Tang, primarily for supporting liver health and addressing syndromes involving "heat" or "stagnation" in Traditional Chinese Medicine (TCM). Its use for infections is based on historical and traditional practices rather than robust scientific validation. In TCM, Bupleurum is believed to help “release the exterior” and “clear heat,” which, in the context of TCM theory, can be interpreted as supporting the body’s response to fevers or mild infections.

Scientific studies on Bupleurum’s direct anti-infective properties are limited and mostly preclinical. Some in vitro and animal studies indicate that compounds in Bupleurum, such as saikosaponins, may modulate the immune system and possess mild anti-inflammatory effects. However, there is insufficient clinical evidence to confirm its efficacy specifically for treating infections in humans. Most modern uses for infection are extrapolated from traditional applications and have not been validated in well-designed clinical trials.

Overall, while Bupleurum’s use for infections is deeply rooted in traditional medicine, the quality of evidence supporting its effectiveness for this indication is low, and it should not be considered a primary or standalone treatment for infections based on current scientific standards.

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