Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Coenzyme Q10 (CoQ10) is supported by scientific evidence for its use in managing hypertension, though the overall strength of evidence is moderate rather than strong. CoQ10 is a naturally occurring antioxidant that plays a crucial role in mitochondrial energy production. Several clinical trials and meta-analyses have investigated its potential antihypertensive effects. A 2007 meta-analysis published in the Journal of Human Hypertension reviewed 12 clinical trials and found that CoQ10 supplementation was associated with a significant reduction in systolic (by about 17 mmHg) and diastolic (by about 10 mmHg) blood pressure in patients with primary hypertension. The proposed mechanism is that CoQ10 improves endothelial function and promotes vasodilation by enhancing nitric oxide availability and reducing oxidative stress.

However, not all studies have shown consistent results, and some more recent research has found smaller or nonsignificant effects. Additionally, the quality of the trials has varied, with some studies having small sample sizes or potential bias. Nonetheless, authoritative sources such as the Mayo Clinic and the American Heart Association acknowledge that CoQ10 appears to have a modest blood pressure-lowering effect and is generally considered safe. CoQ10 is not a first-line treatment for hypertension but may be considered as an adjunct to standard therapy, particularly in patients with mild hypertension or those seeking complementary options. Overall, scientific evidence supports its use, but it should not replace established antihypertensive medications.

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Other ingredients used for Hypertension

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Nature's Sunshine Cellular Energy
Nature's Sunshine Circulatory System
Nature's Sunshine Mega-Chel
Nature's Sunshine SnorEase