Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of Broussonetia species, particularly Broussonetia papyrifera (paper mulberry), for the treatment of hepatitis is primarily rooted in traditional medicine systems, especially in East Asia. In Traditional Chinese Medicine (TCM), the bark and root extracts of Broussonetia have been used historically for their purported liver-protective and detoxifying properties. Descriptions of its use can be found in classical herbal literature, where it has been indicated for "clearing heat" and "removing dampness," concepts often associated with liver ailments like hepatitis in TCM theory.

Scientific research into the hepatoprotective effects of Broussonetia is limited but emerging. Some in vitro and animal studies have shown that extracts from Broussonetia papyrifera may exhibit antioxidant and anti-inflammatory activities, which could theoretically benefit liver health or mitigate liver injury. However, these studies are preliminary, and there is a lack of robust clinical trials in humans demonstrating efficacy against hepatitis specifically. No major pharmacological or clinical guidelines endorse its use for hepatitis, and the evidence supporting its use in this context is not strong.

In summary, while Broussonetia has a tradition of use for liver-related conditions including hepatitis, scientific validation is limited. Its application for hepatitis remains primarily justified by traditional practices rather than by high-quality modern research.

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