Evidence supporting the use of: Vitamin B2
For the body system: Hepatic System
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin B2, also known as riboflavin, plays an essential role in many metabolic processes, including those occurring in the liver (hepatic system). It acts as a cofactor for various enzymes involved in redox reactions, energy production, and the metabolism of fats, drugs, and steroids—many of which occur in hepatic tissue. Riboflavin is required for the synthesis of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are crucial for the functioning of the electron transport chain and for detoxification pathways in the liver (such as those mediated by cytochrome P450 enzymes).
There is scientific evidence from biochemical studies that riboflavin deficiency impairs liver function, including decreased ability to detoxify certain compounds and impaired energy metabolism. Severe deficiency can lead to hepatic dysfunction, but this is rare in developed countries. However, there is limited direct clinical evidence to support supplemental riboflavin as a treatment for liver disease or to specifically enhance hepatic function in otherwise healthy individuals. Most support for its use comes from its established role as an essential vitamin required for overall metabolic health, including liver function, rather than from targeted clinical studies on liver outcomes.
In summary, while riboflavin is necessary for proper hepatic metabolism, the evidence for using supplemental vitamin B2 specifically to "support" the hepatic system beyond correcting a deficiency is limited. Its use is scientifically grounded at the basic metabolic level, but clinical validation for hepatic support is moderate at best.
Other ingredients that support Hepatic System
amino acidsartichoke
barberry
berberine
black garlic
bovine
bovine liver
broccoli
bupleurum falcatum
turmeric
curcumin
d-glucarate
dandelion
epigallocatechin gallate (EGCG)
fructose
garlic bulb
gentian root
gooseberry
green tea
hesperetin
kale
L-glutathione
L-methionine
L-ornithine
lecithin
liquid liver fractions
Matcha
Milk thistle
N-acetyl-cysteine (NAC)
Naringin
Niacin (vitamin B3)
Niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
olive
ox bile
pantethine
parsley
phenolic compounds
phosphatidylcholine
phospholipids
pumpkin
riboflavin (vitamin B2)
Schisandra chinensis
silymarin
sulforaphane glucosinolate
tocotrienols
Trimethylglycine (TMG)
Triphala
vitamin B
Water
Watercress
Zinc
jiaogulan
punarnava
picrorhiza kurroa
lingzhi
bile salt
ferulic acid
ganoderma
polyphenols
trace minerals
herbal blend (proprietary)
Algae
AMP-activated protein kinase (AMPK)
apigenin
Antrodia camphorata
Arginine carglumate
AHCC
andrographolide
alpha-lipoic acid
ampelopsin
animal protein
black seed
borotutu
Brassica
Beef liver
baicalein
Basidiomycota
boldo
betanin
berry
bitter principals
bile acid
Bupleurum
Boerhavia diffusa
cholic acid
carqueja
catalpol
Coenzyme A
capillary artemisia
chlorogenic acid
Curcuminoid
cynarin
cruciferous
capers
chanca piedra
Curcuma
Chinese thoroughwax
corilagin
cynaropicrin
dihydromyricetin
DL-Methionine
dehydrocholic acid
dihydrolipoic acid
dithiolthiones
eriocitrin
egg
Eclipta
emblicanin
fungus
fringetree
flavonolignan
Ginsenosides
Gypenoside
gamma-glutamylcysteine
gallate
glucose
Glycocholic acid
Glycyrrhetinic acid
Guggulsterones
Glycyrrhizin
Gentiana manshurica
Glycochenodeoxycholic acid
isosilybin
isoliquiritigenin
Jurubeba
Kutkins
Maslinic acid
mangiferin
Monoterpenes
Myricetin
Mushroom
Naringenin
Nigella seed
Nobiletin
Oxymatrine
ornithine L-aspartic acid
Phyllanthus
Puerarin
Phenylpropanoids
Picroside
Pentacyclic triterpenoids
Polydatin
Phthalides
pu-er tea
polymethoxylated flavones
Plukenetia volubilis
Scoparia dulcis
Silybin
Salvianolic acid
Schisandrins
Silydianin
Silychristin
Schizandrol A
Silybum
S-allylcysteine
Sesamin
Sulforaphane
Terminalia
Terpenoids
Thymoquinone
Taxifolin
Thistle
Taurochenodeoxycholic acid
Taurocholic acid
Triterpenes
Taurodeoxycholic acid
Taraxacum
Theabrownin
Wogonin
Xanthohumol
Xanthorrhizol
Yin Chen
Other body systems supported by Vitamin B2
BloodBrain
Digestive System
Eyes
Gastrointestinal Tract
Hepatic System
Immune System
Mitochondria
Nerves
Skin