Evidence supporting the use of: Terminalia
For the body system: Hepatic System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Terminalia, particularly species such as Terminalia chebula, Terminalia bellirica, and Terminalia arjuna, have a long history of use in traditional Ayurvedic and Unani medicine for supporting liver (hepatic) health. In Ayurveda, formulations like "Triphala," which contains Terminalia chebula and Terminalia bellirica, are prescribed for detoxification and to promote liver function. Traditional uses include claims of hepatoprotective, antioxidant, and anti-inflammatory effects, and these species are often employed to treat jaundice, hepatitis, and other liver disorders in folk medicine.

While traditional use is robust, scientific validation is moderate. Some preclinical studies (in vitro and animal models) have demonstrated potential hepatoprotective effects, such as reduced liver enzyme levels, antioxidant activity, and protection against chemically induced liver injury. For example, extracts of Terminalia chebula have shown protective effects in rodent models of liver toxicity. However, well-designed human clinical trials are limited, and the existing evidence is not sufficient to fully endorse its efficacy by modern medical standards.

In summary, the use of Terminalia for hepatic support is primarily justified by strong traditional use and some supportive but preliminary scientific evidence. Further clinical research is needed to establish its safety and effectiveness for liver health in humans.

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