Baccharoides anthelmintica (syn. Vernonia anthelmintica) has a history of use in traditional medicine systems, particularly in Ayurveda and folk practices in India. Traditional healers have used its seeds and extracts for a range of ailments, with primary uses focused on skin diseases, anti-parasitic treatment (as the name "anthelmintica" suggests), and sometimes for general pain and inflammation. There are occasional mentions in ethnobotanical literature of its use for headache relief, typically as part of a multi-herb preparation or as a topical application for headache or general pain. However, these references are sparse and not well-documented in authoritative pharmacopeias or classical Ayurvedic texts as a primary remedy for tension headaches.

Scientifically, there is little to no direct research evaluating the efficacy of Baccharoides anthelmintica specifically for tension headaches or headache disorders. Most pharmacological studies have focused on its anti-inflammatory, antimicrobial, and antioxidant properties. Given that tension headaches are often associated with muscle tightness and inflammation, it is possible that the general anti-inflammatory effects observed in laboratory studies could provide some rationale for its traditional use, but this remains speculative and unproven. Overall, the link between Baccharoides anthelmintica and tension headache relief is primarily based on traditional or anecdotal use rather than robust scientific evidence.