Evidence supporting the use of: Cysteine
For the body system: Hair

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cysteine is an amino acid that plays a critical role in the structure and health of hair. It is a key component of keratin, the fibrous protein that makes up the majority of hair, skin, and nails. The sulfur-containing side chain in cysteine allows for the formation of disulfide bonds, which are responsible for the strength, rigidity, and shape of hair fibers. Several laboratory and clinical studies have explored the impact of cysteine supplementation on hair growth and quality. For example, some research indicates that supplementation with L-cysteine, often in combination with other micronutrients such as vitamins B6 and B7 (biotin), can improve hair density and reduce hair loss in individuals experiencing telogen effluvium or diffuse hair thinning. However, while there is a plausible biological rationale and some supportive clinical evidence, the overall quality and size of clinical trials are limited, and results are sometimes mixed. No major adverse effects have been reported with cysteine supplementation at commonly used doses. In summary, the use of cysteine to support the hair system is grounded in solid biological mechanisms and some clinical support, justifying a moderate evidence rating.

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