Evidence supporting the use of: Aerva lanata
For the health condition: Gonorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Aerva lanata, commonly known as mountain knotgrass, is traditionally used in various systems of folk and Ayurvedic medicine, particularly in India, for the treatment of urinary tract infections and venereal diseases, including gonorrhea. The use of Aerva lanata for gonorrhea is primarily based on ethnobotanical reports and traditional practices, where its decoctions or extracts are administered to alleviate symptoms associated with genitourinary infections. Several ethnomedical surveys conducted in regions such as Tamil Nadu and Kerala document its use by traditional healers for this purpose.

However, the scientific validation for its use specifically against Neisseria gonorrhoeae (the causative agent of gonorrhea) is limited. Some in vitro studies have demonstrated that crude extracts of Aerva lanata possess general antibacterial activity, but direct evidence against N. gonorrhoeae is lacking. The plant contains phytochemicals such as flavonoids, alkaloids, and saponins, which may contribute to its antimicrobial properties, but controlled clinical trials or specific pharmacological studies in the context of gonorrhea are absent.

In summary, while Aerva lanata has a documented traditional use for the management of gonorrhea and genitourinary infections, the evidence supporting its efficacy is largely anecdotal or based on traditional knowledge rather than robust scientific research. Its evidence rating is therefore low to moderate, pending further pharmacological investigation.

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