Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Jiaogulan (Gynostemma pentaphyllum) has a long history of use in traditional Chinese medicine, where it is sometimes referred to as the "immortality herb." Traditionally, it has been used as a general tonic to support overall vitality, including the function of various organ systems such as the adrenal glands and endocrine (hormonal) system, which are key components of the glandular system. Folk uses have focused on its adaptogenic properties—meaning it is believed to help the body adapt to stress and balance bodily processes—though these claims are primarily based on historical usage and anecdotal reports.

While some laboratory and animal studies have suggested jiaogulan may influence hormone levels or exhibit adaptogenic effects, high-quality clinical trials demonstrating clear benefits for the glandular system in humans are lacking. Most of the contemporary interest in jiaogulan focuses on its antioxidant and anti-inflammatory properties, with only indirect support for glandular health. For these reasons, the use of jiaogulan to support the glandular system is mainly justified by tradition rather than robust scientific evidence. The evidence rating is 2, reflecting weak support from traditional use and minimal direct scientific validation for this specific application.

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