Evidence supporting the use of: Oregon grape
For the health condition: Glands (swollen lymph)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Oregon grape (Mahonia aquifolium) has a long history of use in traditional herbal medicine, particularly among Native American groups and later in Western herbalism. Its primary use has been as an antimicrobial, anti-inflammatory, and liver-supportive herb. Swollen lymph glands, often a symptom of infection or immune response, have traditionally been addressed with Oregon grape due to its perceived ability to "cleanse the blood" and support detoxification processes. The root contains berberine, which has known antimicrobial properties, and other alkaloids that may contribute to its effects.

However, direct evidence for Oregon grape specifically reducing swollen lymph nodes is lacking in scientific literature. Its traditional application in this context is likely based on its general use for infections, fevers, and skin conditions—situations where lymph nodes might be swollen. While some herbalists may recommend it for swollen glands, this is not supported by robust clinical trials. The evidence for its efficacy in this area is thus rooted in tradition and case reports rather than scientific validation. The overall evidence rating is low (2 out of 5), as its use is plausible but not directly substantiated by modern research targeting lymphatic swelling specifically.

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