Evidence supporting the use of: Taurocholic acid
For the body system: Gall Bladder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Taurocholic acid is a bile acid naturally synthesized in the liver by conjugating cholic acid with taurine. It plays a physiological role in the emulsification of dietary fats and the absorption of fat-soluble vitamins. In terms of supporting the gallbladder, taurocholic acid’s primary function is as a component of bile, which aids in digestion.

There is some scientific evidence, mostly from animal studies and biochemical research, showing that supplementation with bile acids (including taurocholic acid) can influence bile composition and flow. This may, in theory, support gallbladder function and reduce the risk of gallstone formation by keeping cholesterol in solution. However, there is limited direct clinical research on the use of taurocholic acid supplements specifically for gallbladder health in humans. Most clinical use of bile acids in medicine involves other bile acids, such as ursodeoxycholic acid, for dissolving certain types of gallstones.

Historically, bile extracts and bile acids have been used in traditional medicine, particularly in Chinese and European contexts, to support digestion and liver health. However, the direct use of taurocholic acid as a supplement for gallbladder support is based more on extrapolation from its physiological role than from strong clinical evidence. Thus, while the use is scientifically plausible, robust evidence in humans is lacking, and the current evidence level is modest.

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