Evidence supporting the use of: Goldenseal
For the body system: Gall Bladder

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldenseal (Hydrastis canadensis) has a long history of use in traditional herbal medicine, particularly among Native American tribes and later in Western herbalism. It has commonly been used as a "bitter tonic" to stimulate digestive function and is sometimes included in herbal formulas intended to support the liver and gallbladder. The rationale behind its use for the gallbladder is primarily related to its bitter constituents (notably berberine and hydrastine), which are thought to stimulate bile production and flow, potentially aiding digestion of fats and promoting gallbladder health.

However, while these traditional uses are well-documented, there is little to no scientific evidence from clinical trials to specifically support goldenseal's efficacy for gallbladder disorders or function. Most scientific studies focus on goldenseal's antimicrobial properties or its effects on the immune system. No robust clinical studies have directly assessed its impact on gallbladder health, bile production, or prevention of gallstones. Thus, while its use is justified by tradition, the evidence strength is low, and it is not endorsed by mainstream medicine for this specific purpose.

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